3U STEM CELL RESEARCH AND TISSUE ENGINEERING

Tissues in our bodies can become damaged through age, injury or disease, and treatment typically focuses on replacing the damaged tissue. The new field of tissue engineering, or regenerative medicine, is a radically different approach which looks to encourage healing and promote regeneration. It does that by creating scaffolds of biomaterials that support the growth of cells. And once the tissue has been regenerated, the scaffold can melt away.

 

Through the 3U STEM CELL AND TISSUE ENGINEERING research collaboration, researchers from RCSI, DCU and Maynooth University are working on a project to regenerate tissue of the cornea, the clear transparent ‘dome’ in the eye. The goal is to improve transplant options for people who have suffered corneal damage. The project combines expertise in bioscaffolds from RCSI with research into corneal stem cells in DCU and an understanding at Maynooth University of immunology, or how the immune system reacts to transplanted material.

 

By its nature, the area of tissue engineering and regenerative medicine relies on input from many disciplines, and the cornea is a complex structure. But the strength and capabilities in the team will allow them to take on the challenge.

 

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Researchers

  • Dr Finbarr O’Sullivan; DCU, National Institute for Cellular Biotechnology
  • Dr Kevin Kavanagh; Maynooth University; Department of Biology
  • Professor Fergal O’Brien; RCSI; Professor of Bioengineering & RegenerativeMedicine; Department of Anatomy
  • Professor Martin Clynes; DCU, National Institute for Cellular Biotechnology, School of Biotechnology
  • Dr. Clair Gallagher; DCU; National Institute for Cellular Biotechnology
  • Mr William Power; Royal Victoria Eye and Ear Hospital and RCSI; Consultant Ophthalmic Surgeon
  • Mr Vincent Lynch; DCU; National Institute for Cellular Biotechnology; School of Biotechnology
  • Dr William Murphy; DCU; National Institute for Cellular Biotechnology and Medical and Scientific Director, Irish Blood Transfusion Service
  • Ms Sandra Shaw; Irish Blood Transfusion Service
  • Dr Niall Barron; DCU, Director of National Institute for Cellular Biotechnology
  • Professor Conor Murphy; RCSI; Department of Ophthamology
  • Dr Paula Meleady; DCU, National Institute for Cellular Biotechnology
  • Dr Colin Clarke; DCU DCU; National Institute for Cellular Biotechnology
  • Dr Ryan McCoy; RCSI; Department of Anatomy
  • Dr Andrew Cameron; RCSI; Department of Anatomy
  • Dr Andreas Heise; DCU; School of Chemical Sciences
  • Dr Garrett McGuinness; DCU; School of Mechanical and Manufacturing Engineering
  • Dr Bernard Mahon; Maynooth University; Department of Biology
  • Dr Joan Ni Gabhann; RCSI; Honorary Lecturer, Department of Biochemistry

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