Type 2 diabetes poses a very serious threat in Ireland. Already hundreds of thousands of Irish people have the condition, in which cells in the body become insensitive to the hormone insulin and blood sugar levels are poorly controlled. That in turn increases the risk of disabling complications such as heart disease, blindness, kidney failure and limb amputation.
The 3U DIABETES Consortium aligns a number of interlinked areas of research into this chronic and costly condition. Researchers in Maynooth University are teasing out the molecular mechanisms by which cells become insensitive to insulin, while experts at DCU can view the issue from a more whole-body level, and RCSI offers the clinical perspective and samples from patients with diabetes.
3U DIABETES is developing a platform in the lab that uses human tissues to mimic the development of diabetes in humans. Crucially, the lab model will offer a test-bed for chemical compounds developed at Maynooth University that show potential for improving blood sugar control. The platform offers an important route for evaluating potential drugs and therapies work before deciding whether to move them into costly clinical trials.
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3U PARTNERSHIP’s 4th Annual Conference – Current Challenges in Diabetes Research will take place on 15 January 2016 in the Royal College of Surgeons in Ireland.
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Type 2 diabetes poses a very serious threat in Ireland. Already hundreds of thousands of Irish people...
Tissues in our bodies can become damaged through age, injury or disease, and treatment typically focuses on replacing…
Every moment, billions of proteins are interacting with each other in and on your cells to make your body work. Capturing…
Approximately one in three people in Ireland will develop cancer over their lifetime…
The 3U Centre of Excellence in Neurodegeneration (COEN) brings together three established and internationally-competitive Centres…