Dr. Annette Byrne leads the RCSI Laboratory for Tumour Biology and Molecular Imaging based in the Royal College of Surgeons in Ireland. Having gained a PhD in Cell Biology (Understanding the role of apoptosis during mammalian preimplantation development),
Dr Byrne was awarded the John Kerner fellowship in Gynaecologic Oncology from the University of California, San Francisco. During this period she was engaged in the elucidation of novel angiogenesis targets important in the development of ovarian cancer, as well as screening in vivo activity of novel therapeutics. Subsequently, Dr Byrne was recruited as Scientist by Pharmacyclics Inc, a medium sized pharmaceutical company in California’s ‘silicon valley’ to investigate the mechanisms of action of a new class of radiation/ chemotherapy sensitizer drugs under clinical development.
In 2003 Dr Byrne relocated to New York where she was employed as Senior Scientist in a small Biotech Start-up, Angion Biomedica Corp, whose main focus was developing therapeutics which manipulated angiogenesis signaling pathways.
Dr Byrne returned to Ireland in 2005 to the position of Principal Investigator at University College Dublin’s Conway Institute. During this three year engagement she was instrumental in establishing Ireland’s first comprehensive Tumour Xenograft Facility and translational In Vivo Imaging activities.
Dr Byrne joined RCSI in 2008 as tenured Lecturer Physiology and Principal Investigator, Tumour Biology/Molecular Imaging. Dr Byrne was promoted to Senior Lecturer in 2013.
For list of Research Publications click here
Briefly describe what your current job entails?
Teaching physiology to graduate entry medical students and running a research group focused on the discovery of new treatments and biomarkers for colorectal, breast and brain cancer.
Have there been any recent developments in your career?
I was awarded a Science Foundation Ireland Career Development Award in 2014 to develop new biomarkers to help personalize treatment for colorectal cancer patients. Please check out our website www.coloforetell.ie for more info.
Why did you choose this particular career?
Originally, I was fascinated by reproductive physiology which led me into working on ovarian cancer and … well, the rest is history!
What career might you have chosen if you weren’t in your current one?
I was offered a place on a drama studies course after my leaving cert so maybe I’d be on the stage!
Where are you from originally?
Do you have any hobbies?
Theatre, drinking craft beers amd I am about to do a sea fishing course in Spiddal…
What public figure do you most admire and why?
Can he be dead? If so.. Samuel Beckett
What kind of music do you like?
Deep house techno and low-fi garage music coming from the brooklyn music scene.